Sign In: 2025 Human Cell Atlas General Meeting

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7HCA Regional Networks: Cross-regional synergies Meeting
8Genetic Diversity Collaboration between Asia and Latin America
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Monday, June 9, 2025
Tuesday, June 10, 2025
Wednesday, June 11, 2025
Thursday, June 12, 2025

8:00 AM - 9:00 AM

Exhibition Area

Registration

9:00 AM - 9:05 AM

Main Hall - Auditorium

Welcome Remarks

Speakers:

Shyam Prabhakar
Jay Shin

9:05 AM - 9:50 AM

Main Hall - Auditorium

State of HCA

Speakers:

Aviv Regev
Sarah Teichmann

9:50 AM - 10:50 AM

Main Hall - Auditorium

Session 1: Roadmaps for Building Atlases

Session Chair: John Randell
Speakers:

Alexandra-Chloe Villani
Gary Reynolds and Shyam Prabhakar: Immune Cell Atlas and Data Ecosystem
Ed Lein: Creating and annotating a new community standard human and cross-species brain cell atlas
Muzlifah Haniffa: Assembling the Developmental Cell Atlas

This session is sponsored by 10x Genomics.

11:20 AM - 12:20 PM

Main Hall - Auditorium

Session 2: Spatial

Session Chair: Holger Heyn

Speakers:

Holger Heyn
Stefania Giacomello: Get n from 1: spatial host-microbiome interactions at the transcriptome level
Mingyao Li: AI-driven smart spatial omics
Zhenyu Xiao: Towards Understanding Early Human Embryonic Development: From Implantation to Gastrulation
Arutha Kulasinghe
Yanyi Huang: Barcoding schemes for spatial in situ sequencing and hybridization

This session is sponsored by Illumina.

12:20 PM - 12:30 PM

Main Hall - Auditorium

UNESCO:HCA Partnership Announcement

Speakers:

John Randell
Aviv Regev
Sarah Teichmann
Casimiro Vizzini

1:55 PM - 2:45 PM

Main Hall - Auditorium

Keynote Day 1

Session Chair: Jay Shin

Speaker:

Soumya Raychaudhuri

2:45 PM - 3:38 PM

Main Hall - Auditorium

Technology Showcase Day Part I

Session Chair: Shyam Prabhakar

Speakers:

Framing Talk
Michael Schnall-Levin (10x Genomics): Powering the Next Generation of Atlasing
Darren Segale (Illumina): Illumina Spatial Technology
Arif Khan and Charlie Lee (AWS): AWS in Research

4:10 PM - 5:00 PM

Main Hall - Auditorium

Technology Showcase Part II

Session Chair: Jay Shin

Speakers:

Yunica Liu (SeekGene Bioscience): Explore More with Every Single Cell: SeekGene’s All-in-One Solutions for Multi-Omics and Spatial Biology
Todd Dickinson (Stellaromics): The Next Dimension of Discovery: Advancing Spatial Biology in 3D
George Emaunel (Vizgen): Pioneering the Next Era of Spatial Biology with MERFISH 2.0 and the MERSCOPE UltraTM Platform
Charlie Roco (Parse Biosciences): A New Era of Biology with Scaled Up Single Cell
Giovanna Prout (Scale Biosciences): Your partner for the future of HCA: from millions to billions of cells

5:10 PM - 6:10 PM

Main Hall - Auditorium

Breakout Session:

Disease - Designing Flagship Projects

Breakout Session Leaders:

Musa Mhlanga and Vinicus Maracaja-Coutinho

Breakout Room 1

Breakout Session:

Spatial - Technologies

Breakout Session Leaders:

Anna Pascual Reguant and Yutaka Suzuki

This Breakout Session Room is brought to you by Stellaromics.

Breakout Room 2

Breakout Session:

Spatial - Computational & Algorithms Challenges

Breakout Session Leaders:

Grace Yeo and Shyam Prabhakar

Breakout Room 4

Breakout Session:

Diversity & Equity: Single cell genetics and somatic mutation

Breakout Session Leaders:

Joseph Powell and Nicole Soranzo

This Breakout Session Room is brought to you by Oxford Nanopore.

.

6:20 PM - 6:35 PM

Main Hall - Auditorium

Atrandi Biosciences Technology Talk

Day 1 Closing

6:35 PM - 8:35 PM

Exhibition Area

Poster Rotation #1 and Exhibition Reception

The opening reception is sponsored by Atrandi Biosciences.

8:00 AM - 9:00 AM

Exhibition Area

Registration

9:00 AM - 9:05 AM

Main Hall - Auditorium

Welcome Remarks Day 2

9:05 AM - 9:55 AM

Main Hall - Auditorium

Keynote Day 2

Session Chair: Jay Shin

Speaker:

Ge Gao

10:20 AM - 11:50 AM

Main Hall - Auditorium

Session 3: Diversity and Equity

Session Chair: Partha Majumder

Speakers:

Shyam Prabhakar and Sophia George
Jay Shin
Patricia Severino
Christian Happi: Genomic Surveillance and Characterization of Microbial Threats Facilitates Early Detection and Containment of Disease Outbreaks in West Africa
Youssef Idaghdour: The impact of inter-ethnic variation on the host response to falciparum malaria
Yukinori Okada: Statistical genetics in population, individual, and single cell resolutions

This session is sponsored by Roche.

.

1:20 PM - 2:38 PM

Main Hall - Auditorium

Technology Showcase Part III

Session Chair: Piero Carninci

Speakers:

Framing Talk
Patrick Bogard (Roche): Introduction to Sequencing by Expansion (SBX)
Patrick Murphy (Oxford Nanopore Technologies): Advancing Spatial and Single Cell Transcriptomics with Oxford Nanopore Sequencing
Rakshit Chaudhary (Bruker): From Pixels to Pathways: Transforming Discovery with Bruker Spatial Biology
Maybelline Giam (Element): High-Dimensional Biology: Advancing Single-Cell and Spatial Multiomics with AVITI24TM
Zohar Shipony (Ultima Genomics): Driving large-scale single cell studies with transformative sequencing economics
Xiaohui Man (BD Biosciences): Level up your research with comprehensive and complete single-cell multiomics solutions BD Rhapsody™
Sujatha Narayanankutty (Singleron): Pushing Boundaries: Discovering Signals Missed by Standard Single Cell RNA Sequencing

2:38 PM - 3:53 PM

Main Hall - Auditorium

Session 4: Disease

Session Chair: Senjuti Saha

Speakers:

Senjuti Saha: Understanding Diseases in a Changing World Through the Human Cell Atlas
Christopher Moxon: Opportunities and barriers to studying the Blood-Brain Barrier in human cerebral malaria
Lei Zhang: Tracing T Cell Lineages and Dynamics in Gastrointestinal Cancer Immunotherapy
Jong-Il Kim
Jinyue Liu: Spatial architecture of autism pathogenesis during early development

This session is sponsored by Helmsley.

.

4:25 PM - 5:25 PM

Main Hall - Auditorium

Breakout Session:

Disease & Diversity - Autoimmune, Infectious disease

Breakout Session Leaders:

Ponpan Matangkasombut Choopong and Jong-Eun Park

Breakout Room 1

Breakout Session:

Disease & Diversity - Cancer

Breakout Leaders:

Harikrishna Nakshatri and Mariana Boroni
Breakout Session Summary and Key Questions

This Breakout Session Room is brought to you by Stellaromics.

Breakout Room 2

Breakout Session:

Disease & Diversity - Neuro

Breakout Session Leaders:

Xiaoqun Wang and Nirmala Rayan

Breakout Room 4

Breakout Session:

Disease & Diversity - Metabolic

Breakout Leaders:

Boxiang Liu and Yulia Medvedeva

This Breakout Session Room is brought to you by Oxford Nanopore.

.

5:35 PM - 6:05 PM

Main Hall - Auditorium

Closing Panel

6:05 PM - 6:15 PM

Main Hall - Auditorium

Day 2 Closing Remarks

Speakers:

Aviv Regev
Sarah Teichmann
Jay Shin
Shyam Prabhakar

6:15 PM - 8:15 PM

Exhibition Area

Poster Rotation #2 and Exhibitor Reception

9:00 AM - 12:00 PM

Breakout Room 2

Unlocking Cellular Insights: AWS Cloud Solutions for Advanced Omics and Generative AI in Research

Join us for an interactive workshop that bridges cutting-edge cloud computing with advanced omics research and AI innovation. This hands-on session will demonstrate how AWS cloud solutions can accelerate your single-cell analysis workflows while introducing practical applications of generative AI in research settings. Participants will learn how to access and analyze data from AWS Open Data, leveraging AWS services such as AWS HealthOmics. Through guided examples, we'll showcase how to manage complex genomic workflows, and innovative ways to integrate generative AI models with biological research. Whether you're a computational biologist, wet lab researcher, or bioinformatician, you'll leave this workshop with practical knowledge to implement cloud-based solutions that can transform your research capabilities. The session is designed for both cloud beginners and experienced users, with a focus on collaboration, and research acceleration. Bring your laptops and let's go build.

This workshop is in-person only. Please note that you must register for the HCA General Meeting and indicate you would like to attend the AWS Workshop when prompted.

There is no additional cost to attend this workshop.

Individuals that have already completed registration can indicate if they would like to attend the workshop by modifying their registration: View or modify an existing registration.

This workshop is sponsored by AWS.

9:00 AM - 12:30 PM

10x Genomics Pte Ltd

10x Genomics Open House: Foundation for Spatial Biology

This half-day event is designed to equip you with foundational knowledge for spatial projects, explore cutting-edge spatial analysis techniques like advanced cell segmentation, and provide exclusive insights from our CTO along with a manufacturing facility tour. It's a comprehensive session for single cell customers looking to enhance their analysis with spatial capabilities. This event will be hosted at 10x Genomics.

Complimentary transportation will be provided from SingHealth Academia to the 10x Genomics office in the morning, with a return trip to SingHealth Academia scheduled at noon.

Seats are limited to the first 50 guests - register now to secure your seat.

12:30 PM - 1:30 PM

Main Hall - Auditorium

Breakout Session:

HCA data portal, metadata and file formats for spatial omics

Breakout Session Leader: Nils Gehlenborg

1:30 PM - 3:25 PM

Main Hall - Auditorium

HCA Regional Networks Meeting, Part 1

The HCA Regional Networks will meet the afternoon of 11 June and will feature speakers from the HCA Middle East, Africa, Asia, and Latin America Regional Networks. The meeting will highlight the progress and opportunities unique to each Regional Network, explore opportunities for knowledge sharing and collaboration, as well as discuss ways to address gaps and regional challenges.

This meeting is open to all attendees, both in person and virtual.

Individuals that have already completed registration can indicate if they would like to attend the workshop by modifying their registration: View or modify an existing registration.

Speakers:

Ayah Al-Rawni: HCA Archive and Regional Networks
Jones Gyamfi: Exploring tumor microenvironment heterogeneity of triple negative breast cancers via single-cell transcriptomics
Ankita Chatterjee: Immunological Consequences of Smoking
Quan Nguyen: Multimodal data integration across single cells, tissues, cohorts and populations
Khanh Do: Metabolic Signaling Dysregulation in Alzheimer’s Disease: Insights from Single-Cell RNA Sequencing.
Woong-Yang Park
Lan Jiang: Scaling Natural and Disease Cohorts Through Innovation and Shared Data Governance

3:55 PM - 4:55 PM

Main Hall - Auditorium

HCA Regional Networks Meeting, Part 2

The HCA Regional Networks will meet the afternoon of 11 June and will feature speakers from the HCA Middle East, Africa, Asia, and Latin America Regional Networks. The meeting will highlight the progress and opportunities unique to each Regional Network, explore opportunities for knowledge sharing and collaboration, as well as discuss ways to address gaps and regional challenges.

This meeting is open to all attendees, both in person and virtual.

Individuals that have already completed registration can indicate if they would like to attend the workshop by modifying their registration: View or modify an existing registration.

Speakers:

Drew Neavin: Curation of diversity demographics in single-cell atlases
Yulia Medvedeva: Building a Multimodal Single-Cell Atlas of Immune Dysregulation in T2D: Insights from a Multi-Ancestry Russian Cohort
Tim Stuart: Scaling single-cell chromatin analysis with regulatory element modules
Varodom Charoensawan: Cellular Complexity and Systemic Immune Profiles Across Ancestral Diversity in Thailand and Mainland SouthEast Asia
Yasuhiro Murakawa: Advancing single-cell transcriptomics: sharing 5' scRNA-seq tools and data to empower the community
Vinicius Maracaja-Coutinho: The single-cell research environment in Chile: general overview and opportunities
Patricia Severino: Single-Cell Research in Brazil: Landscape, Challenges, and Future Directions

4:55 PM - 5:30 PM

Cross-Regional Discussion

Closing Remarks

9:00 AM - 1:00 PM

NTU@OneNorth, Auditorium 302

Genetic Diversity Collaboration between Asia & Latin America

This session aims to bring together scientific networks from Asia and Latin America. Participants get to engage in cross-regional dialogue, explore opportunities for knowledge sharing and collaboration, as well as discuss ways to address gaps and regional challenges.

This meeting is open to all attendees, both in person and virtual.

Individuals that have already completed registration can indicate if they would like to attend by modifying their registration: View or modify an existing registration.

Please note that this session will be located at NTU@One-North, Auditorium 302

Address: NTU@one-north, 11 Slim Barracks Rise, Singapore 138664

9:00 - 10:00 AM - HCA Latin America Session

Session Moderators:

Alexandre Denadai Souza, Mariana Boroni, Patricia Severino, Vinicius Maracaja-Coutinho, and Yesid Cuesta

Speakers:

Sueli Mieko Oba Shinjo: Effect of metabolic changes on cognitive decline by single cell transcriptomics
Jaqueline Cruz Geraldis
Katherine Athayde Teixeira de Carvalho
Adriana F. Paes Leme: Unraveling Head and Neck Cancer from Initiation to Progression Using Spatial and Single-Cell Proteomics
Geraldo A. Passos: Single-cell transcriptomics reveals the heterogeneity of medullary thymic epithelial cells
Carlos Serrano
Marcelo Mori: Single-Cell Transcriptomics Maps Adipose Tissue Macrophage Diversity and Links Specific Subsets to Type 2 Diabetes
Kenneth J. Gollob
Walderez Ornelas Dutra: Single-cell technology applied to the study of human neglected cardiomyopathies
Robson Carvalho
Valentina Parra
Diana Jennifer Moreno Garcia
Liliana Lopez Kleine: Single Cell data analysis at Universidad Nacional de Colombia
Jorge Duitama: Single cell transcriptomic analysis for refractory epilepsy patients in Colombia
Geysson Javier Fernandez Garcia
Rafael Parra Medina
Ricardo Chinchilla
Carlos Ortiz Ramirez
Yalbi Balderas
Lucia Spangenberg: Indigenous and African ancestry in the Uruguayan population

10:00 - 10:15 AM: Coffee Break

10:15 - 11:00 AM: Latin America + Asia Discussion

11:00 - 11:25 AM: Coffee Break

11:25 - 12:15 PM: HCA Asia Session

Speakers:

Christine Joh: Elucidating gut immune signatures in Korean inflammatory bowel disease cohorts
Sowon Choi: High-resolution spatial profiles across multiple cancers in Korea
Jingweng Fang: scPERT: A Single-Cell Perturbation Enhanced Representation Transformer Through Supervised Fine-Tuning Using Thaoe-100M
Reema Baskar: Spatial Profiling of Colorectal Cancer Extracellular Milieu Reveals Axes of Immunosuppression and Inflammation
Xiaohan Xu: Construct a Pan-Paedcancer Cell Atlas
Go Sato: Multi-layered single-cell genomics deconvolutes biological mechanisms underlying clonal hematopoiesis and mitochondrial heteroplasmy in infectious & autoimmune diseases

Illumina, Northtech Building

Illumina Multiomics Showcase: Manufacturing Tour & Networking Session

This tour grants you exclusive access to Illumina's manufacturing and R&D facility in Singapore. Join the tour to discover how their sequencers and consumables are made. Illumina’s R&D team will also share the latest multi-omic tools that are available and currently in development.

If you are interested in attending, please email amea@illumina.com with the subject line “HCA Tour” and someone from their team will contact you to coordinate further details.

Time Zone: (UTC+08:00) Singapore [Change Time Zone]

Please contact meetings@humancellatlas.org if you have questions about this or other HCA meetings.

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