Registration

Coffee + Light Bites provided

Welcome Remarks Day 2

Keynote Day 2

Session Chair: Holger Heyn

Speaker:

• Ge Gao: Towards a Rational-Designed Regulatory Language Model
   

Coffee Break + Light Bites

Meet the Editor Session: 
Madhura Mukhopadhyay (Nature Methods)
Located at the Registration Desk

Session 3: Diversity and Equity

Session Chair: Partha Majumder

Speakers:

• Shyam Prabhakar, Sophia George, and Kian Hong Kock: Updates on the Diversity Task Force Recommendations and the Way Forward
• Jay Shin: Mapping Human Diversity with Spatial: The Next Chapter in the Human Cell Atlas Asia
• Patricia Severino: Why Diversity Matters: Expanding Discovery Through Regional Genomics and Researcher Inclusion
• Christian Happi: Genomic Surveillance and Characterization of Microbial Threats Facilitates Early Detection and Containment of Disease Outbreaks in West Africa
• Youssef Idaghdour: The impact of inter-ethnic variation on the host response to falciparum malaria
• Yukinori Okada: Statistical genetics in population, individual, and single cell resolutions

This session is sponsored by Roche.

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Lunch with Poster Rotation #2 & Exhibitor Viewing
 

Meet the Editor Session: 
Madhura Mukhopadhyay (Nature Methods)
Located at the Registration Desk

Technology Showcase Part III

Session Chair: Piero Carninci

Speakers:

• Patrick Bogard (Roche): Introduction to Sequencing by Expansion (SBX)
• Patrick Murphy (Oxford Nanopore Technologies): Advancing Spatial and Single Cell Transcriptomics with Oxford Nanopore Sequencing
• Rakshit Chaudhary (Bruker): From Pixels to Pathways: Transforming Discovery with Bruker Spatial Biology
• Jens Durruthy Durruthy (Element): High-Dimensional Biology: Advancing Single-Cell and Spatial Multiomics with AVITI24TM
• Zohar Shipony (Ultima Genomics): Driving large-scale single cell studies with transformative sequencing economics
• Xiaohui Man (BD Biosciences): Level up your research with comprehensive and complete single-cell multiomics solutions BD Rhapsody™
• Sujatha Narayanankutty (Singleron): Pushing Boundaries: Discovering Signals Missed by Standard Single Cell RNA Sequencing

Session 4: Disease

Session Chair: Senjuti Saha

Speakers:

• Senjuti Saha: Understanding Diseases in a Changing World Through the Human Cell Atlas
• Christopher Moxon: Opportunities and barriers to studying the Blood-Brain Barrier in human cerebral malaria 
• Lei Zhang: Tracing T Cell Lineages and Dynamics in Gastrointestinal Cancer Immunotherapy
• Jong-Il Kim: Mapping the Single-Cell Landscape of Inflammatory Diseases: From Disease-Specific Insights to Systemic Understanding
• Jinyue Liu: Spatial architecture of autism pathogenesis during early development

This session is sponsored by Helmsley.

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Coffee Break + Light Bites

Breakout Session:

Disease & Diversity - Cancer
 

Breakout Leaders:

• Harikrishna Nakshatri and Mariana Boroni
  Breakout Session Summary and Key Questions

 This Breakout Session Room is brought to you by Stellaromics.

Breakout Session:

Disease & Diversity - Metabolic
 

Breakout Leaders:

• Boxiang Liu and Yulia Medvedeva
  Breakout Session Summary and Key Questions

  This Breakout Session Room is brought to you by Oxford Nanopore.

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Breakout Session:

Disease & Diversity - Neuro

Breakout Session Leaders:

• Xiaoqun Wang and Nirmala Rayan
  Breakout Session Summary and Key Questions

Breakout Session:

Disease & Diversity - Autoimmune, Infectious disease
 

Breakout Session Leaders:

• Ponpan Matangkasombut Choopong and Jong-Eun Park
  Breakout Session Summary and Key Questions

2025 General Meeting Call to Action and Reflections

Session Chair: Jay Shin

Speakers:

• Holger Heyn
• Muzlifah Haniffa
• Alexandra-Chloe Villani
• Shyam Prabhakar

Day 2 Closing Remarks

Speakers:

• Aviv Regev
• Sarah Teichmann
• Jay Shin
• Shyam Prabhakar

Poster Rotation #2 and Exhibitor Reception
Canapés + Drinks provided

Registration

Coffee + Light Bites provided

Unlocking Cellular Insights: AWS Cloud Solutions for Advanced Omics and Generative AI in Research

Join us for an interactive workshop that bridges cutting-edge cloud computing with advanced omics research and AI innovation. This hands-on session will demonstrate how AWS cloud solutions can accelerate your single-cell analysis workflows while introducing practical applications of generative AI in research settings. Participants will learn how to access and analyze data from AWS Open Data, leveraging AWS services such as AWS HealthOmics. Through guided examples, we'll showcase how to manage complex genomic workflows, and innovative ways to integrate generative AI models with biological research. Whether you're a computational biologist, wet lab researcher, or bioinformatician, you'll leave this workshop with practical knowledge to implement cloud-based solutions that can transform your research capabilities. The session is designed for both cloud beginners and experienced users, with a focus on collaboration, and research acceleration. Bring your laptops and let's go build.

This workshop is in-person only. Please note that you must register for the HCA General Meeting and indicate you would like to attend the AWS Workshop when prompted. 

There is no additional cost to attend this workshop.

Individuals that have already completed registration can indicate if they would like to attend the workshop by modifying their registration: View or modify an existing registration.  
 

This workshop is sponsored by AWS.

10x Genomics Open House: Foundation for Spatial Biology

This half-day event is designed to equip you with foundational knowledge for spatial projects, explore cutting-edge spatial analysis techniques like advanced cell segmentation, and provide exclusive insights from our CTO along with a manufacturing facility tour. It's a comprehensive session for single cell customers looking to enhance their analysis with spatial capabilities. This event will be hosted at 10x Genomics.

Complimentary transportation will be provided from SingHealth Academia to the 10x Genomics office in the morning, with a return trip to SingHealth Academia scheduled at noon.

Seats are limited to the first 50 guests - register now to secure your seat.

Final Lunch with Poster & Exhibitor Viewing
 

Breakout Session:

HCA data portal, metadata and file formats for spatial omics

Breakout Session Leader: Nils Gehlenborg
Breakout Session Summary and Key Questions

HCA Regional Networks Meeting, Part 1

The HCA Regional Networks will meet the afternoon of 11 June and will feature speakers from the HCA Middle East, Africa, Asia, and Latin America Regional Networks. The meeting will highlight the progress and opportunities unique to each Regional Network, explore opportunities for knowledge sharing and collaboration, as well as discuss ways to address gaps and regional challenges. 

This meeting is open to all attendees, both in person and virtual. 

Individuals that have already completed registration can indicate if they would like to attend the workshop by modifying their registration: View or modify an existing registration. 

Session Chairs: Tim Stuart & Jasmine Plummer

Speakers:

• Ayah Al-Rawni: HCA Archive and Regional Networks
• Jones Gyamfi: Exploring tumor microenvironment heterogeneity of triple negative breast cancers via single-cell transcriptomics
• Ankita Chatterjee: Immunological Consequences of Smoking: Comprehensive scRNAseq profiling of 1.2 million PBMCs across 619 Asians in AIDA consortium
• Quan Nguyen: Multimodal data integration across single cells, tissues, cohorts and populations
• Khanh Do: Metabolic Signaling Dysregulation in Alzheimer’s Disease: Insights from Single-Cell RNA Sequencing.
• Woong-Yang Park: Korean Single-Cell Research Network: National Projects, Data Resources, and Global Collaboration
• Lan Jiang: Scaling Natural and Disease Cohorts Through Innovation and Shared Data Governance

Coffee Break + Light Bites

HCA Regional Networks Meeting, Part 2

The HCA Regional Networks will meet the afternoon of 11 June and will feature speakers from the HCA Middle East, Africa, Asia, and Latin America Regional Networks. The meeting will highlight the progress and opportunities unique to each Regional Network, explore opportunities for knowledge sharing and collaboration, as well as discuss ways to address gaps and regional challenges. 

This meeting is open to all attendees, both in person and virtual. 

Individuals that have already completed registration can indicate if they would like to attend the workshop by modifying their registration: View or modify an existing registration. 

Session Chairs: Quan Nguyen & Mariana Boroni

Speakers:

• Drew Neavin: Curation of diversity demographics in single-cell atlases
• Yulia Medvedeva: Building a Multimodal Single-Cell Atlas of Immune Dysregulation in T2D: Insights from a Multi-Ancestry Russian Cohort
• Tim Stuart: Scaling single-cell chromatin analysis with regulatory element modules
• Varodom Charoensawan: Cellular Complexity and Systemic Immune Profiles Across Ancestral Diversity in Thailand and Mainland SouthEast Asia 
• Yasuhiro Murakawa: Advancing single-cell transcriptomics: sharing 5' scRNA-seq tools and data to empower the community
• Vinicius Maracaja-Coutinho: The single-cell research environment in Chile: general overview and opportunities
• Patricia Severino: Single-Cell Research in Brazil: Landscape, Challenges, and Future Directions

Cross-Regional Discussion

Closing Remarks

 

Genetic Diversity Collaboration between Asia & Latin America

This session aims to bring together scientific networks from Asia and Latin America. Participants get to engage in cross-regional dialogue, explore opportunities for knowledge sharing and collaboration, as well as discuss ways to address gaps and regional challenges. 

This meeting is open to all attendees, both in person and virtual. 

Individuals that have already completed registration can indicate if they would like to attend by modifying their registration: View or modify an existing registration. 
 

Please note that this session will be located at NTU@One-North, Auditorium 302 (Level 3)

Address: NTU@one-north, 11 Slim Barracks Rise, Singapore 138664

9:00 - 10:20 AM - HCA Latin America Session

Session Moderators:

Alexandre Denadai Souza, Mariana Boroni, Patricia Severino, Vinicius Maracaja-Coutinho, and Yesid Cuesta

Speakers:

• Sueli Mieko Oba Shinjo: Effect of metabolic changes on cognitive decline by single cell transcriptomics
• Jaqueline Cruz Geraldis: From Cells to Clinics: Mapping Cellular Diversity Underlying Clinical Phenotypes of the Sclerotic Hippocampus
• Adriana F. Paes Leme: Unraveling Head and Neck Cancer from Initiation to Progression Using Spatial and Single-Cell Proteomics
• Geraldo A. Passos: Single-cell transcriptomics reveals the heterogeneity of medullary thymic epithelial cells
• Carlos Serrano: Single-cell RNA sequencing and its insights into plaque atherosclerosis
• Marcelo Mori: Single-Cell Transcriptomics Maps Adipose Tissue Macrophage Diversity and Links Specific Subsets to Type 2 Diabetes
• Kenneth J. Gollob: Discovering Biomarkers and Mechanisms of Therapy Response through Single-Cell Profiling of Tumor and Blood in Cancer
• Walderez Ornelas Dutra: Single-cell technology applied to the study of human neglected cardiomyopathies
• Valentina Parra: The Advanced Genomic Unit at the Faculty of Chemical and Pharmaceutical Sciences, University of Chile: A Platform for Growth and Collaboration in Genomics across Latin America
• Diana Jennifer Moreno Garcia: Implementation of a single-cell sequencing strategy for the characterization of intratumoral heterogeneity in tissue samples from patients with triple-negative breast cancer pre- and post-cytoreduction therapy
• Liliana Lopez Kleine: Single Cell data analysis at Universidad Nacional de Colombia
• Jorge Duitama: Single cell transcriptomic analysis for refractory epilepsy patients in Colombia
• Geysson Javier Fernandez Garcia: Expanding the Human Cell Atlas: Contributions from Latin American Studies of Neurovascular Disease
• Ricardo Chinchilla: CICICA: An Opportunity to Expand Genetic Diversity in Central American Cancer Studies
• Carlos Ortiz Ramirez: The role of non-coding RNA in adaptation: from cells to populations
• Yalbi Balderas: Yes, I Use Human Cell Atlas Repositories—and Build My Own: Exploring Cell Plasticity through Public Data and Custom Integration
• Lucia Spangenberg: Mapping disease at cellular resolution: Uruguayan admixed cohorts for single-cell and spatial transcriptomics

10:20 - 10:45 AM:  Latin America + Asia Discussion

10:45 - 11:15 AM: Coffee Break + Light Bites

11:15 - 12:45 PM:  HCA Asia Session

Speakers:

• Jingweng Fang: scPERT: A Single-Cell Perturbation Enhanced Representation Transformer Through Supervised Fine-Tuning Using Thaoe-100M
• Herawati Sudoyo: Mapping Immune Cell Diversity Across Indonesia:  Integrating Genetic, Lifestyle and Collaborative Insights
• Hideki Ueno: Multi-platform Single-Cell Analysis to Elucidate the Human Liver Immunology
• Christine Joh: Elucidating gut immune signatures in Korean inflammatory bowel disease cohorts
• Sowon Choi: High-resolution spatial profiles across multiple cancers in Korea
• Reema Baskar: Spatial Profiling of Colorectal Cancer Extracellular Milieu Reveals Axes of Immunosuppression and Inflammation
• Xiaohan Xu: Construct a Pan-Paedcancer Cell Atlas
• Go Sato: Multi-layered single-cell genomics deconvolutes biological mechanisms underlying clonal hematopoiesis and mitochondrial heteroplasmy in infectious & autoimmune diseases

Illumina Multiomics Showcase: Manufacturing Tour & Networking Session

This tour grants you exclusive access to Illumina's manufacturing and R&D facility in Singapore. Join the tour to discover how their sequencers and consumables are made. Illumina’s R&D team will also share the latest multi-omic tools that are available and currently in development.

If you are interested in attending, please email amea@illumina.com with the subject line “HCA Tour” and someone from their team will contact you to coordinate further details.